10 health conditions to watch out for in your 50s

The common health challenges and how to minimise your risks

Friday 17 February 2023
Crop unrecognizable male doctor with stethoscope

As we age, our bodies undergo numerous changes, and we become more susceptible to certain health conditions. In particular, people in their 50s face an increased risk for a variety of ailments. This blog post will outline eight common health conditions that you're much more likely to encounter in your 50s, and provide advice on how to minimize your risks. By arming yourself with this knowledge, you can take proactive steps to maintain your health and vitality in your golden years.


Osteoarthritis, a degenerative joint disease, results from the progressive breakdown of cartilage in the joints. This condition can cause pain, stiffness, and reduced mobility. As you enter your 50s, your risk of developing osteoarthritis increases, particularly in weight-bearing joints such as the knees, hips, and spine.

Man in Blue and Black Crew Neck Shirt in Pain

Research suggests that engaging in regular physical activity can help prevent the onset and progression of osteoarthritis by maintaining joint health and promoting weight management (1). Low-impact exercises like swimming, cycling, or walking can keep your joints strong and flexible without causing excessive strain. A study published in the journal Arthritis Care & Research found that weight loss can reduce the risk of knee osteoarthritis in middle-aged women (2). Therefore, it's essential to maintain a healthy weight to alleviate stress on your joints. Additionally, incorporating anti-inflammatory foods, such as fatty fish, nuts, and leafy greens, into your diet may help counteract inflammation associated with osteoarthritis (3).

Cardiovascular Disease

Cardiovascular disease (CVD) encompasses a range of conditions affecting the heart and blood vessels, including coronary artery disease, heart attacks, and strokes. Risk factors for CVD tend to increase with age, making it a significant concern for those in their 50s.

To protect your heart, adopt lifestyle changes that promote cardiovascular health. Adhering to the American Heart Association's "Life's Simple 7" guidelines has been shown to reduce the risk of developing heart disease by 50% (4). These guidelines include regular exercise, a balanced diet, maintaining a healthy weight, avoiding smoking, and managing blood pressure, cholesterol, and blood sugar levels. Furthermore, effectively managing stress and having regular check-ups with your GP can help you stay on top of your cardiovascular health.

Type 2 Diabetes

Strawberry and Glucose Reading Device on White Table

Type 2 diabetes is a chronic condition where your body cannot use insulin effectively, leading to high blood sugar levels. People in their 50s are more susceptible to developing type 2 diabetes due to factors like age-related muscle loss and reduced insulin sensitivity. According to a study published in The Lancet, the risk of developing type 2 diabetes increases substantially after the age of 40, with a peak incidence occurring in the 50-59 age group (5).

To reduce your risk, adopt a healthy lifestyle that includes regular exercise, a balanced diet, and weight management. A study in the New England Journal of Medicine found that participants who engaged in lifestyle interventions, such as a low-calorie, low-fat diet, and moderate-intensity exercise, reduced their risk of developing type 2 diabetes by 58% (6).

Another crucial aspect of managing type 2 diabetes risk is maintaining a healthy weight. Research published in the journal Diabetologia suggests that weight loss of 5-10% can significantly reduce the risk of developing type 2 diabetes in middle-aged individuals (7). In addition to weight loss, incorporating foods with a low glycemic index, such as whole grains, legumes, and non-starchy vegetables, into your diet can help manage blood sugar levels and decrease your risk of diabetes (8).

It is important to keep an eye on your blood sugar levels, and if you're at risk, consult with your GP about getting screened regularly for diabetes. You should also visit your GP as soon as possible if you experience some of the main diabetes symptoms such as blurred vision, feeling very tired or peeing more frequently than usual, especially at night.

Menopause-Related Health Issues


For women, the transition into menopause brings about hormonal changes that can lead to various health issues. These can include hot flashes, night sweats, mood swings, and sleep disturbances. Moreover, the decline in estrogen levels during menopause increases the risk of osteoporosis and heart disease. According to research published in the journal Menopause, up to 80% of women experience vasomotor symptoms, such as hot flashes and night sweats, during their menopause transition (9).

To alleviate menopause-related symptoms, talk to your GP about hormone replacement therapy (HRT) and other treatment options. A study in the journal Climacteric found that HRT effectively reduced vasomotor symptoms, improved sleep quality, and enhanced overall quality of life in postmenopausal women (10). However, HRT may not be suitable for everyone, and potential risks and benefits should be carefully discussed with your GP.

Additionally, incorporate calcium and vitamin D into your diet as it has been shown to be important in maintaining bone health during menopause and reducing the risk of osteoporosis (11). Adopting a Mediterranean-style diet, which is rich in fruits, vegetables, whole grains, and healthy fats, can also significantly reduce cardiovascular risk in postmenopausal women.

Prostate Health


Issues men in their 50s face an increased risk of prostate health issues, such as benign prostatic hyperplasia (BPH) and prostate cancer. BPH, also known as an enlarged prostate, can lead to urinary difficulties, while prostate cancer is the second most common cancer in men. According to a study published in the journal European Urology, the prevalence of BPH increases significantly with age, affecting approximately 50% of men aged 51-60 years (12).

To maintain prostate health, eat a nutrient-rich diet, exercise regularly, and maintain a healthy weight. Research published in the journal Cancer Epidemiology, Biomarkers & Prevention suggests that a diet high in fruits, vegetables, and whole grains, and low in red and processed meats, may help reduce the risk of prostate cancer (13). Engaging in regular physical activity has also been shown to lower the risk of BPH and prostate cancer. (14).

Also, talk to your doctor about prostate cancer screenings and ways to minimize your risk. The NHS recommends that men with an average risk of prostate cancer should discuss the pros and cons of screening with their healthcare provider, starting at age 50 (15). If you are over 50, you can also request a prostate-specific antigen (PSA) test from your GP which can help detect early prostate cancer. Men with a higher risk, such as those with a family history of prostate cancer or Black men, should have this conversation with your GP at age 45.

For more information, you can take a look at our full article on the topic: Prostate cancer: signs and symptoms to watch out for.

Age-Related Macular Degeneration (AMD)

Anonymous oculist examining vision of patient on eye screener

AMD is a leading cause of vision loss in people aged 50 and older. This condition affects the macula, a part of the retina responsible for central vision. As AMD progresses, it can lead to blurriness, distortion, or even a blind spot in your central vision. The exact cause of AMD is still unclear, although it has been linked to high blood pressure, smoking or having a family history of AMD.

While AMD is not painful and will not change the appearance of your eyes, it can affect your day to day activities such as reading, watching TV, driving or recognising faces.

To lower your risk of developing AMD, adopt a diet rich in antioxidants, such as vitamins C and E, zinc, and lutein. These nutrients can be found in fruits, vegetables, nuts, and fish. Also, protect your eyes from harmful UV rays by wearing sunglasses, and avoid smoking, as it can accelerate the progression of AMD. Regular eye exams are essential for early detection and treatment of this condition.

Hearing Loss

Pensive man listening to answer in paper cup phone

Hearing loss is a common issue for people in their 50s, and it can have a significant impact on their quality of life. Age-related hearing loss, or presbycusis, occurs gradually as the tiny hair cells in the inner ear become damaged or die over time. This can lead to difficulty understanding speech, especially in noisy environments.

To preserve your hearing, avoid exposure to loud noises, such as concerts or using power tools without ear protection. Limit the use of headphones at high volumes, and have your hearing checked regularly by an audiologist. If you're experiencing hearing difficulties, consider using hearing aids or other assistive devices to improve your communication.

If you think your hearing is getting gradually worse, it is advisable to see a GP as some instances of hearing loss may be caused by something easily treatable such as an ear infection or earwax build-up.

Cognitive Decline and Dementia

Human brain anatomical model on a plate

Cognitive decline is a natural part of the aging process, but some individuals in their 50s may experience more significant cognitive changes, increasing their risk for dementia, such as Alzheimer's disease. Dementia is a general term for a decline in cognitive ability severe enough to interfere with daily life. Alzheimer's is the most common cause of dementia, accounting for 60-80% of cases.

One study published in the journal Neurology found that people with a higher cardiovascular risk score in middle age were more likely to have poorer cognitive function later in life (16). To maintain your cognitive health, engage in regular mental exercises, such as puzzles, reading, or learning a new skill. Physical activity, social engagement, and a healthy diet also play vital roles in supporting cognitive function. The MIND diet, which combines aspects of the Mediterranean and DASH diets, has been specifically designed to promote brain health and reduce the risk of dementia (17). In addition, prioritize quality sleep, as research suggests that poor sleep can contribute to cognitive decline (18).

Depression and Anxiety

Worried young woman covering face with hand

Mental health is just as important as physical health, and individuals in their 50s can be more vulnerable to depression and anxiety. Factors such as hormonal changes, chronic health conditions, and life stressors can contribute to the onset of these mental health issues. According to a study published in JAMA Psychiatry, the prevalence of major depression increases during midlife, with 7.5% of individuals aged 45-64 years experiencing a major depressive episode (19).

To support your mental well-being, cultivate a strong support network of friends and family, engage in activities you enjoy, and practice stress-reduction techniques like mindfulness, meditation, or yoga. A meta-analysis published in the journal JAMA Internal Medicine found that mindfulness-based interventions, such as mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT), can significantly reduce symptoms of anxiety and depression (20). Physical activity can also play a crucial role in managing depression and anxiety. In fact, even a small amount of regular exercise can help reduce the risk of developing depression.

Don't hesitate to seek professional help from a therapist or counselor if you're struggling with depression or anxiety. The NHS offers free talking therapy services which you can access by speaking to your GP or getting in touch with the talking therapies service directly.

Sarcopenia and Muscle Loss

Crop black woman doing exercises with dumbbells

Sarcopenia, the age-related loss of muscle mass and function, can lead to reduced strength, mobility, and overall physical performance. The risk of developing sarcopenia increases in your 50s, making it crucial to prioritize muscle health as you age. Muscle loss can contribute to a higher risk of falls, frailty, and a decreased quality of life.

Research suggests that engaging in regular resistance training can help counteract age-related muscle loss and improve physical function (21). To maintain and improve muscle mass, incorporate strength training exercises, such as weightlifting or bodyweight exercises, into your fitness routine at least twice a week. In addition to regular exercise, proper nutrition is vital for muscle health. A diet rich in protein, healthy fats, and complex carbohydrates can support muscle maintenance and growth. Some research also indicates that consuming adequate amounts of vitamin D and omega-3 fatty acids may help reduce the risk of sarcopenia (22).

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